Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171533 | 0.82 | MAPT (0.52) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL27541790 | 0.81 | MAPT (0.55) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL8715608 | 0.81 | GABRP (0.55) | MAPTALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL3281749 | 0.79 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL266614 | 0.78 | MAPT (0.63) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL28304255 | 0.75 | MAPT (0.58) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL8773390 | 0.75 | CSNK2A2 (0.62) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL13347724 | 0.75 | MAPT (0.63) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL23334588 | 0.72 | MAPT (0.73) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL7806804 | 0.72 | KCNA5 (0.60) | MAPTKDM4EALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861242-B1 | HETEROCYCLIC FUNGICIDES | AVENTIS CROPSCIENCE UK LTD (GB) | 2001-05-30 | — | — | EP | disclosed |
| US-6034121-A | AGRICULTURE | AGREVO UK LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |
| EP-0861242-A1 | HETEROCYCLIC FUNGICIDES | AgrEvo UK Limited (GB) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997013762-A1 | HETEROCYCLIC FUNGICIDES | AGREVO UK LIMITED (GB) | 1997-04-17 | — | — | WO | disclosed |