Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509317 | 1.00 | ITGB3 (0.47) | ITGB3ITGB1ITGAVITGB6KMT2A | |
| SCHEMBL7797656 | 0.88 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGB6KMT2A | |
| SCHEMBL6492125 | 0.88 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGB6KMT2A | |
| SCHEMBL6491361 | 0.86 | ITGB3 (0.60) | ITGB3ITGB1ITGAVITGB6KMT2A | |
| SCHEMBL6491359 | 0.86 | ITGB3 (0.60) | ITGB3ITGB1ITGAVITGB6KMT2A | |
| SCHEMBL6179834 | 0.86 | F2 (0.53) | KMT2AMAPTMEN1HTTALDH1A1 | |
| SCHEMBL27224522 | 0.81 | MEN1 (0.44) | KMT2ATBXAS1MEN1GAASMN1; SMN2 | |
| SCHEMBL27532652 | 0.80 | F10 (0.45) | GAAALDH1A1KDM4EHPGD | |
| SCHEMBL27396676 | 0.79 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGB6KMT2A | |
| SCHEMBL27224515 | 0.79 | F2 (0.46) | KMT2ATBXAS1MEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |