Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492125 | 1.00 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGB6OPRM1 | |
| SCHEMBL7808018 | 0.88 | ITGB3 (0.47) | ITGB3ITGB1ITGAVITGB6MEN1 | |
| SCHEMBL27509317 | 0.88 | ITGB3 (0.47) | ITGB3ITGB1ITGAVITGB6MEN1 | |
| SCHEMBL8329187 | 0.85 | F2 (0.55) | OPRM1F2ESR1ESR2F10 | |
| SCHEMBL27224522 | 0.83 | MEN1 (0.44) | F2MEN1KMT2ACYP3A4CDC7 | |
| SCHEMBL6491322 | 0.82 | ITGB3 (0.56) | ITGB3ITGB1ITGAVITGB6OPRM1 | |
| SCHEMBL6493601 | 0.82 | ITGB3 (0.56) | ITGB3ITGB1ITGAVITGB6OPRM1 | |
| SCHEMBL27396676 | 0.81 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGB6F2 | |
| SCHEMBL27224515 | 0.81 | F2 (0.46) | F2MEN1KMT2AF10PRSS1 | |
| SCHEMBL6533433 | 0.79 | F10 (0.47) | OPRM1F2ESR1ESR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |