Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.35 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813176 | 0.92 | CDK1 (0.52) | CDK1GAATSHRALDH1A1HPGD | |
| Chlorobenzene SCHEMBL23797205 | 0.87 | CDK1 (0.50) | CDK1GAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL116126 | 0.87 | CDK1 (0.55) | CDK1GAATSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL29878397 | 0.87 | CDK1 (0.55) | CDK1GAATSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL7806403 | 0.83 | CDK1 (0.53) | CDK1GAAALDH1A1HTTCYP1A2 | |
| SCHEMBL7806393 | 0.82 | GAA (0.56) | CDK1GAAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL7809237 | 0.81 | CDK1 (0.49) | CDK1GAATSHRALDH1A1HTT | |
| SCHEMBL8111084 | 0.81 | CDK1 (0.47) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL7808101 | 0.79 | GAA (0.47) | CDK1GAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8539307 | 0.78 | GAA (0.44) | CDK1GAATSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971902-B1 | AMINOSULFONYLUREAS WITH HERBICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2001-12-19 | — | — | EP | disclosed |
| US-6329323-B1 | AMINOTRIAZINE DERIVATIVES | ISAGRO RICERCA S.R.L. (IT) | 2001-12-11 | — | — | US | disclosed |