Chlorobenzene

Chlorobenzene

SCHEMBL23797205

COc1cc(OC)nc(NC(=O)NS(=O)(=O)Nc2ccccc2C(=O)N(C)C)n1.Clc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.50
GAA P10253 1/20 0.44
MAPT P10636 2/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NAMPT P43490 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.35
P2RY1 P47900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29878397 0.94 CDK1 (0.55) CDK1GAAMAPTTP53GLA
SCHEMBL116126 0.94 CDK1 (0.55) CDK1GAAMAPTTP53GLA
SCHEMBL7809237 0.89 CDK1 (0.49) CDK1GAAMAPTTP53GLA
SCHEMBL7813176 0.87 CDK1 (0.52) CDK1GAAMAPTTP53GLA
SCHEMBL7808142 0.87 CDK1 (0.55) CDK1GAAMAPTTP53GLA
SCHEMBL7808101 0.86 GAA (0.47) CDK1GAAMAPTTP53GLA
SCHEMBL7801275 0.85 GAA (0.45) CDK1GAAMAPTTP53GLA
SCHEMBL8380205 0.83 GAA (0.51) CDK1GAAMAPTTP53GLA
SCHEMBL8535695 0.83 GAA (0.51) CDK1GAAMAPTTP53GLA
SCHEMBL8111084 0.83 CDK1 (0.47) CDK1GAAMAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3876735-A1 COMPOSITIONS COMPRISING A PYRIDINE CARBOXYLATE HERBICIDE AND A MICROTUBULE ASSEMBLY INHIBITOR HERBICIDE Corteva Agriscience LLC (US) 2021-09-15 EP disclosed