Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | PTPRB | P23467 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | BRD4 | O60885 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857113 | 0.91 | MEN1 (0.55) | HPGDPTPRBHSD17B10MEN1KMT2A | |
| SCHEMBL9808046 | 0.85 | MRGPRX4 (0.52) | HPGDPTPRBHSD17B10MEN1KMT2A | |
| SCHEMBL11829865 | 0.83 | BRD4 (0.59) | BRD4MEN1KMT2AMAOBNPC1 | |
| Hydrochloric Acid SCHEMBL10735781 | 0.80 | MRGPRX4 (0.45) | HPGDPTPRBHSD17B10MEN1KMT2A | |
| SCHEMBL14228548 | 0.79 | BRD4 (0.55) | HPGDBRD4MEN1KMT2AMAOB | |
| SCHEMBL10905417 | 0.79 | MRGPRX4 (0.44) | HPGDPTPRBHSD17B10MEN1KMT2A | |
| SCHEMBL10903897 | 0.79 | L3MBTL1 (0.55) | MEN1KMT2AMRGPRX4MAOBNPC1 | |
| Acetic Acid SCHEMBL402815 | 0.79 | MEN1 (0.55) | MEN1KMT2AMRGPRX4MAOBLMNA | |
| Hydrochloric Acid SCHEMBL10907709 | 0.79 | MRGPRX4 (0.44) | HPGDPTPRBHSD17B10MEN1KMT2A | |
| SCHEMBL27240095 | 0.78 | MEN1 (0.53) | MEN1KMT2AMRGPRX4MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727421-B1 | Agents for improving sleep | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-24 | — | — | EP | disclosed |
| EP-0727421-A1 | Agents for improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0285219-A2 | Method of improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-10-05 | — | — | EP | disclosed |