Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818467 | 0.83 | HTR1A (0.47) | DRD2HTR1A | |
| SCHEMBL7821489 | 0.82 | HTR1A (0.46) | DRD2HTR1A | |
| SCHEMBL7817369 | 0.76 | HTR1A (0.39) | DRD2HTR1A | |
| SCHEMBL31052148 | 0.76 | HTR1A (0.52) | DRD2HTR1A | |
| SCHEMBL7830351 | 0.76 | HTR1A (0.74) | DRD2HTR1A | |
| SCHEMBL31051992 | 0.75 | HTR1A (0.50) | DRD2HTR1A | |
| SCHEMBL7820641 | 0.74 | HTR1A (0.40) | DRD2HTR1A | |
| SCHEMBL7830823 | 0.74 | DRD3 (0.61) | DRD2HTR1A | |
| SCHEMBL7807803 | 0.74 | HTR1A (0.62) | DRD2HTR1A | |
| SCHEMBL31051799 | 0.74 | HTR1A (0.52) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633260-B1 | 2,3-Dihydro-1,4-benzodioxan-5-yl-piperazine derivatives having 5-HT1A-antagonistic activity | DUPHAR INT RES (NL) | 2001-11-07 | — | — | EP | disclosed |
| US-5462942-A | 2,3-dihydro-1,4-benzodioxin-5-yl-piperazine derivatives having 5-HT 1A-antagonistic activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1995-10-31 | — | — | US | disclosed |
| EP-0633260-A1 | 2,3-Dihydro-1,4-benzodioxin-5-yl-piperazine derivatives having 5-HT1A-antagonistic activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1995-01-11 | — | — | EP | disclosed |