Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808245 | 1.00 | LMNA (0.43) | LMNACYP2C19ALDH1A1TAAR1HTR2A | |
| SCHEMBL28159957 | 0.80 | KDM4E (0.34) | LMNACYP2C19ALDH1A1TRPA1SMN1; SMN2 | |
| SCHEMBL9862758 | 0.78 | LMNA (0.35) | LMNACYP2C19ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2812126 | 0.77 | MAPT (0.36) | LMNACYP2C19ALDH1A1TAAR1TRPA1 | |
| SCHEMBL7034905 | 0.75 | TSHR (0.36) | LMNACYP2C19ALDH1A1TDP1MAPT | |
| SCHEMBL10626266 | 0.75 | LMNA (0.33) | LMNACYP2C19ALDH1A1TDP1MAPT | |
| SCHEMBL27193603 | 0.74 | CYP19A1 (0.41) | ALDH1A1HTR2ASMN1; SMN2MAPT | |
| SCHEMBL5912987 | 0.74 | HTT (0.35) | LMNACYP2C19ALDH1A1HTR2AHRH1 | |
| SCHEMBL6033303 | 0.74 | TSHR (0.39) | LMNACYP2C19ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2811184 | 0.73 | MAPT (0.37) | LMNACYP2C19ALDH1A1TRPA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647647-B1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5523437-A | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0647647-A1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-12 | — | — | EP | disclosed |