SCHEMBL7808469

SCHEMBL7808469

CN(C)c1ccc(-c2cc(N)ccc2N(CCO)CCO)o1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809861 0.85 ALDH1A1 (0.34) KDM4EALDH1A1MAPT
SCHEMBL7800638 0.83 ALDH1A1 (0.38) KDM4EALDH1A1MAPT
SCHEMBL7459176 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7812266 0.81 KDM4E (0.38) KDM4EALDH1A1MAPT
SCHEMBL7812181 0.81 ALDH1A1 (0.36) KDM4EALDH1A1MAPT
SCHEMBL7812228 0.79 KDM4E (0.38) KDM4EALDH1A1MAPT
SCHEMBL7812183 0.79 MEN1 (0.32) ALDH1A1
SCHEMBL6573269 0.76 ALDH1A1 (0.43) ALDH1A1MAPT
SCHEMBL7808238 0.76 S100B (0.33) ALDH1A1MAPT
SCHEMBL7805920 0.76 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed