SCHEMBL780850

SCHEMBL780850

c1cc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc(-n2c3ccc(-c4cccc5c4oc4ccccc45)cc3c3cc(-c4cccc5c4oc4ccccc45)ccc32)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
PRKDC P78527 8/20 0.43
GGPS1 O95749 1/20 0.42
PTGES2 Q9H7Z7 1/20 0.39
PRMT5 O14744 1/20 0.39
WDR77 Q9BQA1 1/20 0.39
ATM Q13315 1/20 0.35
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
RXFP1 Q9HBX9 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
PLA2G10 O15496 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
PPARG P37231 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL781463 0.98 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL12153567 0.95 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL13830074 0.94 ALOX5 (0.52) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL15959676 0.93 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL21578764 0.93 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL15959740 0.93 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL781064 0.93 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17562338 0.93 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL781203 0.93 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17885347 0.93 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-12-29 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9419230-B2 Compound for organic optoelectronic device, organic light emitting diode including the same, and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-08-16 US disclosed
US-9419230-B2 Compound for organic optoelectronic device, organic light emitting diode including the same, and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-08-16 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20130292659-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2013-11-07 US disclosed
US-20130292659-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2013-11-07 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885GGPS1 2063/4885
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885GGPS1 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.