Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031125 | 0.99 | HTR1D (0.33) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8035283 | 0.74 | HTR1D (0.32) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8031631 | 0.71 | HTR1D (0.32) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8031123 | 0.71 | HTR1D (0.43) | HTR1DHTR1B | |
| SCHEMBL7798145 | 0.69 | KMO (0.35) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8021863 | 0.68 | KMO (0.34) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8031133 | 0.67 | PTGDR2 (0.37) | HTR1DHTR1B | |
| SCHEMBL10022383 | 0.63 | CYP1A2 (0.40) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL12841361 | 0.63 | CYP1A2 (0.47) | CYP1A2CYP2C9 | |
| SCHEMBL7798270 | 0.63 | HTR1D (0.50) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |