Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805450 | 0.79 | KMT2A (0.44) | KMT2AESR1ESR2PIM1KDM4E | |
| SCHEMBL8713331 | 0.78 | PTPN1 (0.49) | KMT2APIM1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7811469 | 0.77 | KMT2A (0.45) | KMT2AESR1ESR2PIM1KDM4E | |
| SCHEMBL7811460 | 0.76 | KDM4E (0.42) | KMT2AESR1ESR2PIM1KDM4E | |
| SCHEMBL7809145 | 0.74 | LMNA (0.41) | KMT2AESR1ESR2PIM1KDM4E | |
| SCHEMBL7800035 | 0.73 | CA1 (0.51) | KMT2APIM1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8715528 | 0.72 | TTR (0.42) | KMT2ACA12CA9PTPN1POLB | |
| SCHEMBL2588529 | 0.72 | PIM1 (0.58) | KMT2APIM1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29416622 | 0.72 | PIM1 (0.58) | KMT2APIM1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5680363 | 0.71 | KMT2A (0.42) | KMT2AESR1ESR2PIM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861242-B1 | HETEROCYCLIC FUNGICIDES | AVENTIS CROPSCIENCE UK LTD (GB) | 2001-05-30 | — | — | EP | disclosed |
| US-6034121-A | AGRICULTURE | AGREVO UK LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |
| EP-0861242-A1 | HETEROCYCLIC FUNGICIDES | AgrEvo UK Limited (GB) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997013762-A1 | HETEROCYCLIC FUNGICIDES | AGREVO UK LIMITED (GB) | 1997-04-17 | — | — | WO | disclosed |