SCHEMBL7809188

SCHEMBL7809188

CCCCC(=O)c1ccc(C)cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.66
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
IDO1 P14902 2/20 0.50
TDO2 P48775 2/20 0.50
ALDH1A1 P00352 3/20 0.49
HPGD P15428 2/20 0.49
TSHR P16473 2/20 0.49
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 1/20 0.49
RECQL P46063 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
KMT2A Q03164 3/20 0.48
MAPT P10636 3/20 0.48
LMNA P02545 2/20 0.48
KDM4E B2RXH2 2/20 0.48
KCNH2 Q12809 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8674913 0.93 HTT (0.71) HTTNPC1RAB9AIDO1TDO2
Ethylenediamine SCHEMBL11233243 0.88 HTT (0.64) HTTNPC1RAB9AIDO1TDO2
SCHEMBL8712689 0.86 CSNK2A1 (0.55) HTTNPC1RAB9AALDH1A1HPGD
SCHEMBL14043029 0.84 HTT (0.50) HTTNPC1RAB9AALDH1A1KMT2A
SCHEMBL3659979 0.84 HTT (0.90) HTTALDH1A1HPGDTSHRHSD17B10
SCHEMBL9639259 0.82 HSP90AB1 (0.69) HTTNPC1RAB9AIDO1TDO2
SCHEMBL7800202 0.81 HTT (0.64) HTTNPC1RAB9AALDH1A1HPGD
SCHEMBL11581541 0.81 KMT2A (0.67) HTTNPC1RAB9AIDO1TDO2
SCHEMBL8085885 0.80 HTT (0.58) HTTRAB9AALDH1A1TDP1KMT2A
SCHEMBL9768518 0.80 HTT (0.58) HTTRAB9AALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115698192-B Coating film and article having coating film formed on surface thereof 国立研究开发法人产业技术综合研究所 2023-11-28 CN disclosed
WO-2023198901-A1 NOVEL SUBSTITUTED 4-AMINO-4-OXO-BUT-2-ENYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF SANOFI (FR) 2023-10-19 WO disclosed
WO-2012017204-A1 EFFICIENT AND COST-EFFECTIVE PROCESS FOR THE MANUFACTURE OF AMYL M-CRESOL AESICA PHARMACEUTICALS LIMITED (GB) 2012-02-09 WO disclosed
CN-1117741-C Heterocyclic fungicides AGREVO UK LTD (GB) 2003-08-13 CN disclosed
EP-0861242-B1 HETEROCYCLIC FUNGICIDES AVENTIS CROPSCIENCE UK LTD (GB) 2001-05-30 EP disclosed
US-6034121-A AGRICULTURE AGREVO UK LIMITED (GB) 2000-03-07 US disclosed
CN-1204330-A Heterocyclic fungicides AGREVO UK LTD (GB) 1999-01-06 CN disclosed
EP-0861242-A1 HETEROCYCLIC FUNGICIDES AgrEvo UK Limited (GB) 1998-09-02 EP disclosed
WO-1997013762-A1 HETEROCYCLIC FUNGICIDES AGREVO UK LIMITED (GB) 1997-04-17 WO disclosed