SCHEMBL7809291

SCHEMBL7809291

C[n+]1ccn(CC(=O)Nc2cc(O)c(NS(C)(=O)=O)c(Cl)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
MAPT P10636 3/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2B Q13224 2/20 0.34
ADRB3 P13945 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7157110 0.99 LMNA (0.38) LMNAALDH1A1HPGDTSHRMAPK1
SCHEMBL6946389 0.86 ALDH1A1 (0.40) LMNAALDH1A1HPGDTSHRMAPK1
Hydrochloric Acid SCHEMBL6941302 0.85 ALDH1A1 (0.40) LMNAALDH1A1HPGDTSHRMAPK1
SCHEMBL6572695 0.81 HPGD (0.39) LMNAALDH1A1HPGDTSHRMAPK1
Hydrochloric Acid SCHEMBL5469099 0.80 HPGD (0.39) LMNAALDH1A1HPGDTSHRMAPK1
SCHEMBL7809277 0.74 ALDH1A1 (0.39) LMNAALDH1A1HPGDTSHRMAPK1
SCHEMBL6945544 0.73 LMNA (0.36) LMNAALDH1A1HPGDTSHRCA12
SCHEMBL6946140 0.73 HPGD (0.44) LMNAALDH1A1HPGDTSHRMAPK1
Hydrochloric Acid SCHEMBL7630660 0.73 ALDH1A1 (0.38) LMNAALDH1A1HPGDTSHRMAPK1
Hydrochloric Acid SCHEMBL6938822 0.72 LMNA (0.36) LMNAHPGDTSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066264-A2 NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP claimed
WO-2000042971-A2 NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO claimed
EP-1066264-A2 NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP disclosed
WO-2000042971-A2 NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO disclosed