SCHEMBL7809388

SCHEMBL7809388

Cc1ccc(O)c(-c2c(C)cc(C)cc2C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
TP53 P04637 2/20 0.47
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
TYR P14679 2/20 0.46
POLB P06746 2/20 0.46
CA2 P00918 1/20 0.46
TRPA1 O75762 1/20 0.39
ALOX15 P16050 6/20 0.39
HSD17B10 Q99714 5/20 0.39
CYP2C9 P11712 3/20 0.39
LMNA P02545 3/20 0.39
NR1I2 O75469 1/20 0.39
MIF P14174 1/20 0.39
HTT P42858 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HSPA5 P11021 1/20 0.39
IDO1 P14902 1/20 0.38
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30306159 0.84 TDP1 (0.60) TDP1TP53ALDH1A1SMN1; SMN2POLB
SCHEMBL30704467 0.81 TDP1 (0.47) TDP1TP53ALDH1A1POLBTRPA1
SCHEMBL11233686 0.79 ALDH1A1 (0.59) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL8775719 0.79 ALDH1A1 (0.48) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL31043326 0.76 ALDH1A1 (0.52) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL270433 0.76 ALDH1A1 (0.64) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL29359626 0.76 ALDH1A1 (0.64) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL11865746 0.74 ALDH1A1 (0.61) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL11673542 0.74 ALDH1A1 (0.61) TDP1TP53ALDH1A1SMN1; SMN2TYR
SCHEMBL28427877 0.74 ALDH1A1 (0.61) TDP1TP53ALDH1A1SMN1; SMN2TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721021-B1 Method for the continuous production of a polyethylene material having high strength and high modulus of elasticity NIPPON MITSUBISHI OIL CORP (JP) 2001-07-11 EP disclosed
US-5702657-A DISPERSING A THERMOPLASTIC RESIN FILM IN THE INTERIOR AND/OR SURFACE OF HIGH MOLECULAR WEIGHT POLYETHYLENE FILM NIPPON OIL CO., LTD. (JP) 1997-12-30 US disclosed
EP-0721021-A2 Method for the continuous production of a polyethylene material having high strength and high modulus of elasticity NIPPON OIL CO., LTD. (JP) 1996-07-10 EP disclosed
US-4440893-A ETHYLENE HOMO OR COPOLYMER, IIA OR IIB OXIDE, AND ACETYLENE PEROXIDE COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1984-04-03 US disclosed
US-3974114-A CALCIUM AND LITHIUM STEARATE UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed