SCHEMBL11233686

SCHEMBL11233686

Cc1ccc(O)c(-c2cc(C)cc(C(C)(C)C)c2O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
TYR P14679 2/20 0.59
CA2 P00918 2/20 0.59
POLB P06746 2/20 0.59
HSPA5 P11021 1/20 0.49
CYP2C9 P11712 4/20 0.47
CYP2C19 P33261 3/20 0.47
HIF1A Q16665 2/20 0.47
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
HSD17B10 Q99714 5/20 0.42
CYP2D6 P10635 1/20 0.42
TRPA1 O75762 1/20 0.42
ALOX15 P16050 5/20 0.41
LMNA P02545 3/20 0.41
NR1I2 O75469 1/20 0.41
MIF P14174 1/20 0.41
HTT P42858 1/20 0.41
NFE2L2 Q16236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886301 0.87 SMN1; SMN2 (0.77) ALDH1A1SMN1; SMN2TYRCA2POLB
SCHEMBL30782815 0.87 SMN1; SMN2 (0.77) ALDH1A1SMN1; SMN2TYRCA2POLB
SCHEMBL6866098 0.85 SMN1; SMN2 (0.74) ALDH1A1SMN1; SMN2TYRCA2POLB
Butylated Hydroxytoluene SCHEMBL8979279 0.83 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2TYRCA2POLB
SCHEMBL6567310 0.82 TRPA1 (0.54) ALDH1A1POLBCYP2C9CYP2C19HIF1A
SCHEMBL17126988 0.79 SMN1; SMN2 (0.65) ALDH1A1SMN1; SMN2TYRCA2POLB
SCHEMBL7809388 0.79 TDP1 (0.47) ALDH1A1SMN1; SMN2TYRCA2POLB
SCHEMBL18826296 0.79 TRPA1 (0.56) ALDH1A1SMN1; SMN2POLBCYP2C9CYP2C19
SCHEMBL270433 0.78 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2TYRCA2POLB
SCHEMBL29359626 0.78 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2TYRCA2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936577-A Polyester resin composition 三菱瓦斯化学株式会社 2020-11-13 CN disclosed
WO-2019194117-A1 POLYESTER RESIN COMPOSITION 三菱瓦斯化学株式会社 2019-10-10 WO disclosed
CN-1437630-A Stabilizer mixture CIBA SC HOLDING AG (CH) 2003-08-20 CN disclosed
US-4327176-A IMPACT RESISTANT ACRYLIC ESTER RESIN BINDER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-04-27 US disclosed