Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803010 | 0.81 | CNR2 (0.57) | CNR2CNR1APPSNCACHRM1 | |
| SCHEMBL7803252 | 0.75 | IDO1 (0.45) | CNR2LMNASMN1; SMN2ALOX5 | |
| SCHEMBL7803160 | 0.74 | APP (0.56) | CNR2CNR1APPSNCACHRM1 | |
| SCHEMBL7815554 | 0.73 | HDAC1 (0.49) | CNR2CNR1APPSNCACHRM1 | |
| SCHEMBL7803251 | 0.73 | ALOX5 (0.45) | ALOX5ADRA1D | |
| SCHEMBL2395366 | 0.73 | ALOX5 (0.53) | KDM4EALDH1A1SMN1; SMN2ALOX5 | |
| SCHEMBL31370014 | 0.72 | KMT2A (0.55) | CNR2CNR1APPSNCACHRM1 | |
| SCHEMBL9583818 | 0.72 | HTR2C (0.54) | CNR2CNR1APPSNCACHRM1 | |
| SCHEMBL3855963 | 0.71 | CNR1 (0.53) | CNR2CNR1APPSNCACHRM1 | |
| SCHEMBL17372069 | 0.71 | HTR2C (0.62) | CNR2CNR1APPSNCACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |