Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 3/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808063 | 0.82 | HTR6 (0.50) | HDAC1HDAC8HDAC6CNR1CNR2 | |
| SCHEMBL7809792 | 0.82 | HDAC6 (0.62) | HDAC1HDAC8HDAC6CNR1CNR2 | |
| SCHEMBL7809786 | 0.79 | HDAC3 (0.50) | CNR1CNR2HTR2CKDM4EHDAC3 | |
| SCHEMBL7809187 | 0.79 | HDAC6 (0.58) | HDAC1HDAC8HDAC6CNR1CNR2 | |
| SCHEMBL7803160 | 0.77 | APP (0.56) | HDAC1HDAC8HDAC6CNR1CNR2 | |
| SCHEMBL31370014 | 0.77 | KMT2A (0.55) | CNR1CNR2HTR2CFNTAFNTB | |
| SCHEMBL17372069 | 0.77 | HTR2C (0.62) | CNR1CNR2HTR2CAPPSNCA | |
| SCHEMBL7815558 | 0.76 | LMNA (0.46) | HDAC1HDAC8HDAC6CNR2HDAC3 | |
| SCHEMBL3852360 | 0.74 | KMT2A (0.52) | CNR1CNR2HTR2CFNTAFNTB | |
| SCHEMBL9701802 | 0.74 | HTR6 (0.64) | HDAC1HDAC8HDAC6HDAC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |