⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311902 | 0.83 | RAB9A (0.65) | — | |
| SCHEMBL3180231 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL135037 | 0.77 | CHRM1 (0.54) | — | |
| Methyl Alcohol SCHEMBL28712278 | 0.71 | — | — | |
| SCHEMBL936199 | 0.71 | — | — | |
| SCHEMBL8149330 | 0.71 | — | — | |
| SCHEMBL18605786 | 0.71 | CHRM1 (0.46) | — | |
| SCHEMBL148914 | 0.71 | — | — | |
| SCHEMBL970306 | 0.69 | — | — | |
| SCHEMBL21087581 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961202-B2 | Bis-benzimidazole compounds and methods of using the same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-03-30 | — | — | US | disclosed |
| EP-3710442-A2 | BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME | The Scripps Research Institute (US) | 2020-09-23 | — | — | EP | disclosed |
| US-20190152924-A1 | BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2019-05-23 | — | — | US | disclosed |
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |
| EP-0904313-B1 | ABSOLUTE MOLECULAR WEIGHT POLYMERS AND METHODS FOR THEIR USE | ALCON LAB INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0904313-A1 | ABSOLUTE MOLECULAR WEIGHT POLYMERS AND METHODS FOR THEIR USE | ALCON LABORATORIES, INC. (US) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997045473-A1 | ABSOLUTE MOLECULAR WEIGHT POLYMERS AND METHODS FOR THEIR USE | ALCON LABORATORIES, INC. (US) | 1997-12-04 | — | — | WO | disclosed |
| US-5547663-A | Absolute molecular weight polymers and methods for their use | ALCON LABORATORIES, INC. (US) | 1996-08-20 | — | — | US | disclosed |