Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809479 | 0.81 | KDM4E (0.36) | KDM4EHSD17B10CA1CA2HPGD | |
| SCHEMBL7809628 | 0.80 | KDM4E (0.43) | KDM4EPADI4TDP1 | |
| SCHEMBL7810952 | 0.80 | RXFP1 (0.47) | KDM4EPADI4RXFP1 | |
| SCHEMBL7809564 | 0.77 | CAPN1 (0.46) | KDM4EPADI4HSD17B10HPGDMEN1 | |
| SCHEMBL7811182 | 0.76 | KDM4E (0.43) | KDM4EPADI4HSD17B10HPGDMEN1 | |
| SCHEMBL7816823 | 0.75 | KDM4E (0.65) | KDM4EPADI4HSD17B10HPGDMEN1 | |
| SCHEMBL29612326 | 0.75 | KDM4E (0.65) | KDM4EPADI4HSD17B10HPGDMEN1 | |
| SCHEMBL7809476 | 0.74 | PLA2G7 (0.34) | KDM4EHSD17B10CA1CA2HPGD | |
| SCHEMBL3358803 | 0.67 | FASN (0.40) | KDM4ECA1CA2MCL1ALDH1A1 | |
| SCHEMBL9389330 | 0.67 | KDM4E (0.43) | KDM4ECA1CA2PLA2G7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| US-5430153-A | Insecticides, fungicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-04 | — | — | US | disclosed |
| EP-0533882-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |