Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809648 | 0.83 | LTB4R (0.37) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL7806678 | 0.83 | MAOA (0.44) | PDE10AMAOAMAOBCYSLTR1ALOX5 | |
| SCHEMBL7813413 | 0.82 | MAPT (0.52) | PDE10AMAOAMAOBALOX5KDM4E | |
| SCHEMBL7808099 | 0.80 | MAOB (0.42) | PDE10AMAOAMAOBCYSLTR1CYSLTR2 | |
| SCHEMBL7801990 | 0.78 | CYSLTR1 (0.35) | CYSLTR1CYSLTR2ALOX5ALOX5AP | |
| SCHEMBL7813524 | 0.77 | CYSLTR1 (0.39) | MAOAMAOBCYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL7808151 | 0.75 | CYSLTR1 (0.38) | MAOAMAOBCYSLTR1CYSLTR2KDM4E | |
| SCHEMBL7813459 | 0.73 | LTB4R (0.46) | PDE10ACYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL7801525 | 0.73 | MAPT (0.56) | PDE10ACYSLTR1CYSLTR2ALOX5KDM4E | |
| SCHEMBL7809599 | 0.73 | LTB4R (0.38) | CYSLTR1CYSLTR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |