SCHEMBL7810060

SCHEMBL7810060

CC(C)(C)[Si](C)(C)C(O)CCO

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15285469 0.86
SCHEMBL2076291 0.79 TDP1 (0.33)
SCHEMBL9174410 0.78
SCHEMBL16460151 0.75 CPB2 (0.32)
SCHEMBL2510884 0.74 TSHR (0.39)
SCHEMBL8427781 0.73
SCHEMBL27490107 0.73
SCHEMBL27613015 0.73
SCHEMBL1663096 0.72
SCHEMBL7705963 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708767-B1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LAB (US) 2001-02-14 EP disclosed
EP-0708767-A4 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LAB (US) 1996-10-02 EP disclosed
US-5541333-A TETHERED HAPTEN INTERMEDIATES ABBOTT LABORATORIES (US) 1996-07-30 US disclosed
EP-0708767-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LABORATORIES (US) 1996-05-01 EP disclosed
US-5464746-A Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives ABBOTT LABORATORIES (US) 1995-11-07 US disclosed
WO-1995003296-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LABORATORIES (US) 1995-02-02 WO disclosed