Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810079 | 0.90 | PPARA (0.49) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL9011042 | 0.90 | PPARG (0.47) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7811577 | 0.89 | PPARG (0.49) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7813666 | 0.89 | PPARG (0.52) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7804294 | 0.88 | HPGD (0.39) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7810037 | 0.87 | PPARG (0.50) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7804398 | 0.86 | PPARG (0.49) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7811760 | 0.85 | PPARG (0.49) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7817648 | 0.85 | PPARG (0.49) | PPARGPPARAALDH1A1HPGDNAMPT | |
| SCHEMBL7811630 | 0.85 | PPARA (0.60) | PPARGPPARAALDH1A1HPGDNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |