⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346429 | 0.75 | — | — | |
| SCHEMBL10458261 | 0.74 | — | — | |
| Urea SCHEMBL3126400 | 0.73 | ALOX15 (0.48) | — | |
| SCHEMBL3643770 | 0.73 | — | — | |
| SCHEMBL10949457 | 0.71 | — | — | |
| SCHEMBL4724903 | 0.71 | — | — | |
| SCHEMBL4071209 | 0.71 | — | — | |
| Carbamic Acid SCHEMBL1902701 | 0.71 | ALOX15 (0.46) | — | |
| SCHEMBL20509359 | 0.71 | — | — | |
| SCHEMBL17204677 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574784-B1 | Process for preparing (1'R,3S,4R)4-acylthio azetidinones | PHARMACIA & UPJOHN SPA (IT) | 2001-12-05 | — | — | EP | disclosed |
| US-5399679-A | (1'R,3S,4R)4-acylthio azetidinones | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-03-21 | — | — | US | disclosed |
| US-5360904-A | Process for preparing penem esters | FARMITALIA CARLO ERBA S R L (IT) | 1994-11-01 | — | — | US | disclosed |
| WO-1993025523-A1 | 4-ACYLTHIO AZETIDINONES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-23 | — | — | WO | disclosed |
| EP-0574784-A1 | (1'R,3S,4R)4-acylthio azetidinones | PHARMACIA S.p.A. (IT) | 1993-12-22 | — | — | EP | disclosed |
| EP-0521018-A1 | PROCESS FOR PREPARING PENEM ESTERS | PHARMACIA & UPJOHN S.p.A. (IT) | 1993-01-07 | — | — | EP | disclosed |
| WO-1991014691-A1 | PROCESS FOR PREPARING PENEM ESTERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-10-03 | — | — | WO | disclosed |