SCHEMBL7810375

SCHEMBL7810375

CN(C(=O)OCc1ccccc1)N(S)S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
SIGMAR1 Q99720 1/20 0.46
ABCB1 P08183 1/20 0.46
CTSL P07711 2/20 0.45
CTSB P07858 2/20 0.45
CTSS P25774 2/20 0.45
CTSK P43235 2/20 0.45
LMNA P02545 2/20 0.45
HCAR2 Q8TDS4 1/20 0.45
CCR6 P51684 1/20 0.44
PAX8 Q06710 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23944892 0.86 ALDH1A1 (0.58) ALDH1A1MAPTHPGDTDP1MAPK1
Benzyl Dimethylcarbamate SCHEMBL5134244 0.82 ALDH1A1 (0.62) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL7694380 0.82 ALDH1A1 (0.62) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL2773501 0.82 ALDH1A1 (0.57) ALDH1A1MAPTHPGDTDP1MAPK1
Benzyl Dimethylcarbamate SCHEMBL14031385 0.82 ALDH1A1 (0.62) ALDH1A1MAPTHPGDTDP1MAPK1
Benzyl Dimethylcarbamate SCHEMBL20401678 0.82 ALDH1A1 (0.62) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL448069 0.80 ALDH1A1 (0.55) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL250619 0.80 ALDH1A1 (0.60) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL10994855 0.80 ALDH1A1 (0.55) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL19596303 0.80 ALDH1A1 (0.51) ALDH1A1MAPTHPGDTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727423-B1 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD (KR) 2001-07-25 EP disclosed
EP-0727424-B1 Process for the preparation of sulfonylurea derivatives LUCKY LTD (KR) 2001-06-20 EP disclosed
EP-0613896-B1 Process for the preparation of sulfonylurea derivatives LUCKY LTD (KR) 1998-07-22 EP disclosed
EP-0727424-A2 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1996-08-21 EP disclosed
EP-0727423-A2 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1996-08-21 EP disclosed
US-5534637-A CHEMICAL INTERMEDIATES LUCKY LTD. (KR) 1996-07-09 US disclosed
EP-0602589-B1 Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof LUCKY LTD (KR) 1996-06-26 EP disclosed
US-5468896-A Chemical intermediates for herbicides LUCKY LTD. (KR) 1995-11-21 US disclosed
US-5466854-A From alkyl hydrazine and carbon disulfide LUCKY LTD. (KR) 1995-11-14 US disclosed
US-5416220-A From a dithiocabazate and an ethoxymethylene malonate LUCKY, LTD. (KR) 1995-05-16 US disclosed
US-5405965-A Heating ethylidene dithiocarbazate compound with base LUCKY LTD. (KR) 1995-04-11 US disclosed
EP-0602589-A1 Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof LUCKY LTD. (KR) 1994-06-22 EP disclosed