SCHEMBL2773501

SCHEMBL2773501

O=C(OCc1ccccc1)N(S)S

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
TDP1 Q9NUW8 3/20 0.55
MAPK1 P28482 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
SLC6A2 P23975 1/20 0.55
SLC6A3 Q01959 1/20 0.55
KMT2A Q03164 1/20 0.55
LMNA P02545 3/20 0.50
HCAR2 Q8TDS4 1/20 0.50
CCR6 P51684 1/20 0.49
PAX8 Q06710 1/20 0.49
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448069 0.98 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL10994855 0.86 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL668388 0.86 ALDH1A1 (0.59) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL22262931 0.85 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL8604257 0.82 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL7810375 0.82 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL8167513 0.82 ALDH1A1 (0.50) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL28682509 0.82 ALDH1A1 (0.50) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL17434764 0.81 TDP1 (0.56) ALDH1A1TDP1MAPK1L3MBTL1LMNA
SCHEMBL11692494 0.80 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
CN-117736707-A 230 ℃ resistant high-salt resistant high-density water-based drilling fluid and preparation method and application thereof 中国石油大学(华东) 2024-03-22 CN claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
CN-115160513-B 240 ℃ high-temperature resistant high-salt resistant rigid-flexible blocking agent and preparation method thereof 中国石油大学(华东) 2023-08-01 CN claimed
CN-114605653-A Preparation method and application of biological thermoplastic elastomer replacing SBS 东南大学 2022-06-10 CN claimed
CN-101613489-A A kind of thiofide and preparation method thereof QI ZHANG 2009-12-30 CN claimed
US-20090012199-A1 Photoinitiator anchored to silicate and use thereof to prepare polymer exfolidated silicate nanocomposite NATIONAL SCIENCE FOUNDATION 2009-01-08 US claimed
JP-2007517119-A 2007-06-28 JP claimed
US-20070145625-A1 Process for crosslinking free-radical crosslinkable polymers DOW GLOBAL TECHNOLOGIES INC. (US) 2007-06-28 US claimed
CN-1918236-A Free radical crosslinkable polymer: improved crosslinking process and composition DOW GLOBAL TECHNOLOGIES INC (US) 2007-02-21 CN claimed
EP-1699881-A2 FREE-RADICAL CROSSLINKABLE POLYMERS: IMPROVED PROCESS FOR CROSSLINKING AND COMPOSITIONS The Dow Global Technologies Inc. (US) 2006-09-13 EP claimed
WO-2006055372-A2 PHOTOINITIATOR ANCHORED TO SILICATE AND USE THEREOF TO PREPARE POLYMER EXFOLIATED SILICATE NANOCOMPOSITE CORNELL RESEARCH FOUNDATION, INC. (US) 2006-05-26 WO claimed
WO-2005066280-A2 FREE-RADICAL CROSSLINKABLE POLYMERS: IMPROVED PROCESS FOR CROSSLINKING AND COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-07-21 WO claimed
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US claimed
US-3962304-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA ALDH1A1 1404/4885TDP1 4498/4885MAPK1 2964/4885
US-20090012199-A1 Photoinitiator anchored to silicate and use thereof to prepare polymer exfolidated silicate nanocomposite MSN, NAPA, SELE ALDH1A1 3240/4885TDP1 1572/4885MAPK1 2568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.