Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7821418 | 0.99 | LMNA (0.47) | MAPTALDH1A1L3MBTL1MAPK1LMNA | |
| SCHEMBL7818219 | 0.93 | MAPT (0.50) | MAPTALDH1A1L3MBTL1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL7825487 | 0.92 | MAPT (0.49) | MAPTALDH1A1L3MBTL1MAPK1LMNA | |
| SCHEMBL7811391 | 0.86 | L3MBTL1 (0.44) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL7822198 | 0.85 | L3MBTL1 (0.43) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL7820961 | 0.83 | L3MBTL1 (0.47) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL7821547 | 0.82 | LMNA (0.65) | MAPTALDH1A1MAPK1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL7822581 | 0.81 | LMNA (0.67) | MAPTALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL7811919 | 0.81 | LMNA (0.41) | MAPTALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL7818149 | 0.81 | KDM1A (0.40) | MAPTALDH1A1MAPK1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | claimed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | claimed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | claimed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | claimed |
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | disclosed |