Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.70 |
| ▸ | RORC | P51449 | 16/20 | 0.68 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7945814 | 0.99 | BDKRB2 (0.69) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7810517 | 0.91 | BDKRB2 (0.74) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7812526 | 0.91 | RORC (0.69) | BDKRB2RORC | |
| SCHEMBL7815060 | 0.90 | BDKRB2 (0.66) | BDKRB2RORC | |
| SCHEMBL7810522 | 0.90 | RORC (0.69) | BDKRB2RORC | |
| Hydrochloric Acid SCHEMBL7952857 | 0.90 | BDKRB2 (0.73) | BDKRB2RORCBDKRB1 | |
| Hydrochloric Acid SCHEMBL7954305 | 0.90 | RORC (0.69) | BDKRB2RORC | |
| SCHEMBL7814891 | 0.90 | BDKRB2 (0.77) | BDKRB2RORCBDKRB1 | |
| Hydrochloric Acid SCHEMBL7952866 | 0.90 | RORC (0.68) | BDKRB2RORC | |
| SCHEMBL6939238 | 0.90 | RORC (0.66) | BDKRB2RORCBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |
| EP-0874841-B1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |