SCHEMBL7811060

SCHEMBL7811060

Cc1cccn1Cc1ccc(I)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 6/20 0.41
HDAC6 Q9UBN7 5/20 0.41
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
PKM P14618 1/20 0.38
VEGFA P15692 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
LMNA P02545 2/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28237435 0.84 MAPT (0.57) HDAC8HDAC6CNR1CNR2MAPT
SCHEMBL31590921 0.82 VEGFA (0.54) HDAC8HDAC6MAPTTP53VEGFA
SCHEMBL1563931 0.82 CNR2 (0.49) CNR1CNR2MAPTTP53CYP11B1
SCHEMBL3195921 0.82 ALDH1A1 (0.52) HDAC8HDAC6MAPTTP53LMNA
SCHEMBL12330471 0.81 HDAC8 (0.44) HDAC8HDAC6CNR1CNR2MAPT
SCHEMBL31590652 0.81 HDAC8 (0.43) HDAC8HDAC6MAPTTP53PKM
SCHEMBL12301203 0.78 MAPT (0.58) HDAC8HDAC6MAPTTP53LMNA
SCHEMBL271362 0.78 HDAC8 (0.47) HDAC8HDAC6MAPTTP53PKM
SCHEMBL31590735 0.74 CNR2 (0.46) CNR1CNR2VEGFAEGLN1LMNA
SCHEMBL2056309 0.73 ALDH1A1 (0.50) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040330-A Benzyl pyrrole compound and preparation method and application thereof 深圳技术大学 2025-05-27 CN disclosed
CN-1093536-C 5-lipoxygenase inhibitors PFIZER (US) 2002-10-30 CN disclosed
EP-0787127-B1 5-LIPOXYGENASE INHIBITORS PFIZER (US) 2001-01-03 EP disclosed
US-6063928-A ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, CARDIOTONIC AGENTS PFIZER INC (US) 2000-05-16 US disclosed
US-5883106-A 5-lipoxygenase inhibitors PFIZER INC. (US) 1999-03-16 US disclosed
CN-1169722-A 5-lipoxygenase inhibitors PFIZER (US) 1998-01-07 CN disclosed
EP-0787127-A1 5-LIPOXYGENASE INHIBITORS PFIZER INC. (US) 1997-08-06 EP disclosed
WO-1996011911-A1 5-LIPOXYGENASE INHIBITORS PFIZER INC. (US) 1996-04-25 WO disclosed