Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSB | P07858 | 4/20 | 0.35 |
| ▸ | CTSH | P09668 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809685 | 0.88 | RXFP1 (0.33) | KDM4ECAPN1CTSLCTSBCTSH | |
| SCHEMBL7812988 | 0.88 | MEN1 (0.34) | ALDH1A1CAPN1CTSLCTSBCTSH | |
| SCHEMBL7813850 | 0.87 | AR (0.36) | CAPN1CTSLCTSBCTSHAR | |
| SCHEMBL497120 | 0.85 | CAPN1 (0.39) | CAPN1CSF1R | |
| SCHEMBL7804026 | 0.83 | RXFP1 (0.45) | KDM4ECAPN1 | |
| SCHEMBL7811062 | 0.80 | KDM4E (0.35) | KDM4EGRIN2DGRIN3BALDH1A1GAA | |
| SCHEMBL7810951 | 0.77 | CAPN1 (0.41) | KDM4ECAPN1CTSLCTSBCTSH | |
| SCHEMBL7816789 | 0.74 | CAPN1 (0.42) | CAPN1CTSLCTSBCTSH | |
| SCHEMBL497316 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1GAAHSD17B10CYP1A2 | |
| SCHEMBL7809500 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| US-5430153-A | Insecticides, fungicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-04 | — | — | US | disclosed |
| EP-0533882-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |