Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804026 | 0.81 | RXFP1 (0.45) | KDM4EDAONR4A2LMNAPARP1 | |
| SCHEMBL7804167 | 0.80 | ALDH1A1 (0.46) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7809500 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL29612326 | 0.79 | KDM4E (0.65) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7816823 | 0.79 | KDM4E (0.65) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7813789 | 0.79 | FEN1 (0.39) | KDM4EALDH1A1KMT2ASMN1; SMN2DAO | |
| SCHEMBL7809535 | 0.78 | FEN1 (0.42) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7809669 | 0.78 | DAO (0.40) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7817120 | 0.77 | CAPN1 (0.44) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7803963 | 0.77 | DAO (0.39) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124948-B1 | COMPOSITIONS FOR TREATING HYPERPROLIFERATIVE VASCULAR DISORDERS AND CANCERS | NC BIT INC (KR) | 2017-07-26 | — | — | EP | disclosed |
| US-8106071-B2 | Compositions for treating hyperproliferative vascular disorders and cancers | BIOBUD CO., LTD. (KR) | 2012-01-31 | — | — | US | disclosed |
| US-20100120849-A1 | Compositions for Treating Hyperproliferative Vascular Disorders and Cancers | BIOBUD CO., LTD (KR) | 2010-05-13 | — | — | US | disclosed |
| EP-2124948-A1 | COMPOSITIONS FOR TREATING HYPERPROLIFERATIVE VASCULAR DISORDERS AND CANCERS | Biobud Co., Ltd. (KR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008102932-A1 | COMPOSITIONS FOR TREATING HYPERPROLIFERATIVE VASCULAR DISORDERS AND CANCERS | BIOBUD CO., LTD. (KR) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120849-A1 | Compositions for Treating Hyperproliferative Vascular Disorders and Cancers | MKI67, MYLK, PCNA | KDM4E 2304/4885TDP1 766/4885ALDH1A1 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.