SCHEMBL7809685

SCHEMBL7809685

CSOc1c(C(C)=O)c(=O)[nH]c2c(Cl)cc(C)cc12

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.33
CAPN1 P07384 3/20 0.32
CTSB P07858 3/20 0.32
CTSL P07711 2/20 0.32
CTSH P09668 1/20 0.32
ALOX15 P16050 1/20 0.30
HRH4 Q9H3N8 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7811064 0.88 KDM4E (0.39) CAPN1CTSBCTSLCTSHKDM4E
SCHEMBL7813850 0.86 AR (0.36) RXFP1CAPN1CTSBCTSLCTSH
SCHEMBL7804026 0.82 RXFP1 (0.45) RXFP1CAPN1KDM4E
SCHEMBL7812988 0.82 MEN1 (0.34) CAPN1CTSBCTSLCTSHALOX15
SCHEMBL7809684 0.81 GRIN1 (0.30) CAPN1CTSBCTSLCTSH
SCHEMBL497120 0.77 CAPN1 (0.39) RXFP1CAPN1
SCHEMBL7810951 0.76 CAPN1 (0.41) RXFP1CAPN1CTSBCTSLCTSH
SCHEMBL7816789 0.76 CAPN1 (0.42) RXFP1CAPN1CTSBCTSLCTSH
SCHEMBL7809500 0.75 KDM4E (0.45) KDM4E
SCHEMBL497316 0.73 KDM4E (0.58) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533882-B1 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM KOREA RES INST CHEM TECH (KR) 2001-02-07 EP disclosed
US-5430153-A Insecticides, fungicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-07-04 US disclosed
EP-0533882-A1 2-QUINOLINONE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-03-31 EP disclosed
WO-1992017452-A1 2-QUINOLINONE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-10-15 WO disclosed