SCHEMBL7811141

SCHEMBL7811141

CC(C)n1c(=O)oc2cc(N3C[C@H](CNC(=O)CO)OC3=O)ccc21

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.46
MAOA P21397 3/20 0.46
LMNA P02545 1/20 0.46
PTGS1 P23219 1/20 0.46
CALML3 P27482 1/20 0.46
SDHA P31040 1/20 0.46
F10 P00742 14/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77099 0.85 F10 (0.63) F10
SCHEMBL86996 0.83 F10 (0.46) MAOBMAOALMNAPTGS1CALML3
Hydrochloric Acid SCHEMBL77043 0.82 F10 (0.45) MAOBMAOALMNAPTGS1CALML3
SCHEMBL3150398 0.79 F10 (0.41) F10
SCHEMBL3035195 0.79 MAOA (0.46) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5764674 0.79 MAOA (0.37) MAOBMAOALMNAPTGS1CALML3
SCHEMBL3043495 0.78 MAOA (0.35) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13250948 0.78 MAOB (0.34) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6520209 0.77 MAOA (0.51) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6520202 0.77 MAOA (0.51) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789025-B1 Substituted oxazolidinone and their use as antibacterial medicine BAYER AG (DE) 2001-04-04 EP disclosed
US-5792765-A ANTIBACTERIAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-08-11 US disclosed
EP-0789025-A1 Substituted oxazolidinone and their use as antibacterial medicine BAYER AG (DE) 1997-08-13 EP disclosed