SCHEMBL7811213

SCHEMBL7811213

COC(CN)CNc1cc(=O)c2ccccc2[nH]1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 1/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7817827 0.99 MARS1 (0.42) MARS1CYP1A2GAA
SCHEMBL6601865 0.79 MARS1 (0.43) MARS1CYP1A2GAA
SCHEMBL7807042 0.78 MARS1 (0.65) MARS1
SCHEMBL178915 0.78 MARS1 (0.65) MARS1
Hydrochloric Acid SCHEMBL7992728 0.78 CTSV (0.41) MARS1CYP1A2GAA
Hydrochloric Acid SCHEMBL6601461 0.78 MARS1 (0.42) MARS1CYP1A2GAA
Hydrochloric Acid SCHEMBL7995914 0.74 MARS1 (0.54) MARS1CYP1A2GAA
SCHEMBL5668076 0.73 MARS1 (0.59) MARS1
Ammonia Solution, Strong SCHEMBL5667906 0.72 MARS1 (0.58) MARS1
Hydrochloric Acid SCHEMBL5669755 0.72 MARS1 (0.58) MARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1084110-A1 QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES SMITHKLINE BEECHAM PLC (GB) 2001-03-21 EP disclosed
WO-1999055677-A1 QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES SMITHKLINE BEECHAM PLC (GB) 1999-11-04 WO disclosed