Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7817050 | 0.97 | PIK3CG (0.62) | PIK3CGPIK3CAPIK3CBPLK1RET | |
| SCHEMBL7813159 | 0.87 | PIK3CG (0.57) | PIK3CGPIK3CAPIK3CBPLK1CAMK2D | |
| Water SCHEMBL7809660 | 0.85 | PIK3CG (0.55) | PIK3CGPIK3CAPIK3CBPLK1CAMK2D | |
| SCHEMBL7809826 | 0.84 | PIK3CG (0.57) | PIK3CGPIK3CAPIK3CBPLK1DYRK1A | |
| Water SCHEMBL7816986 | 0.82 | PIK3CG (0.55) | PIK3CGPIK3CAPIK3CBPLK1DYRK1A | |
| SCHEMBL2330123 | 0.79 | PLK1 (0.56) | PIK3CGPIK3CAPIK3CBPLK1CAMK2D | |
| SCHEMBL3513778 | 0.78 | CAMK2D (0.73) | PIK3CGPIK3CAPIK3CBPLK1CAMK2D | |
| SCHEMBL7809747 | 0.78 | CDK1 (0.71) | PIK3CGPIK3CAPIK3CBPLK1CAMK2D | |
| SCHEMBL7817223 | 0.74 | CDK1 (0.66) | PIK3CGPIK3CAPIK3CBPLK1CAMK2D | |
| SCHEMBL7765087 | 0.74 | HDAC3 (0.56) | PIK3CGPIK3CAPIK3CBRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672041-B1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2001-11-14 | — | — | EP | disclosed |
| US-5728708-A | ANTITUMOR AGENTS | NOVARTIS CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0672041-A1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995009853-A1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CIBA-GEIGY AG (CH) | 1995-04-13 | — | — | WO | disclosed |