Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814002 | 0.92 | KMT2A (0.40) | KCNA5SLC6A4HRH3NPC1ALDH1A1 | |
| SCHEMBL7810320 | 0.89 | NPC1 (0.45) | SLC6A4HRH3NPC1ALDH1A1HPGD | |
| SCHEMBL7804350 | 0.84 | AVPR1A (0.44) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL7811731 | 0.79 | NPC1 (0.43) | SLC6A4HRH3NPC1ALDH1A1HPGD | |
| SCHEMBL7810158 | 0.77 | KCNA5 (0.47) | KCNA5NPC1NAMPTALDH1A1HPGD | |
| SCHEMBL7817534 | 0.73 | PTGDR (0.43) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL7817583 | 0.73 | NPC1 (0.44) | NPC1ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL7817391 | 0.71 | MAOB (0.54) | KCNA5SLC6A4HRH3NPC1ALDH1A1 | |
| SCHEMBL7810120 | 0.71 | POLB (0.48) | KCNA5SLC6A4HRH3NPC1ALDH1A1 | |
| SCHEMBL7811522 | 0.69 | ACHE (0.50) | KCNA5ALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |