Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811501 | 0.92 | KMT2A (0.47) | ACHEHTTL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL7811611 | 0.88 | NPC1 (0.56) | ALDH1A1HTTL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL7817608 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTTKMT2AMEN1KDM4E | |
| SCHEMBL7817804 | 0.77 | NPC1 (0.54) | ALDH1A1HTTL3MBTL3L3MBTL1HPGD | |
| SCHEMBL7817391 | 0.76 | MAOB (0.54) | ALDH1A1KCNA5BLMKMT2AMEN1 | |
| SCHEMBL7804380 | 0.74 | KCNA5 (0.52) | ACHEALDH1A1HTTEPHX1L3MBTL3 | |
| SCHEMBL7810120 | 0.73 | POLB (0.48) | ACHEALDH1A1HTTKCNA5BLM | |
| SCHEMBL2603247 | 0.73 | ACHE (0.68) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL14597201 | 0.72 | ACHE (0.61) | ACHEALDH1A1HTTEPHX1L3MBTL3 | |
| SCHEMBL7320518 | 0.72 | ACHE (0.66) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| CN-1094039-A | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |