Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011017 | 0.86 | AVPR1A (0.47) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7813359 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7804350 | 0.85 | AVPR1A (0.44) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7817583 | 0.83 | NPC1 (0.44) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL9010984 | 0.82 | PTGDR (0.47) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7813953 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7817534 | 0.79 | PTGDR (0.43) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7813501 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ACASP3NR1D1 | |
| SCHEMBL9011187 | 0.76 | PTGDR (0.45) | ALDH1A1MEN1KMT2APTGDRPTGDR2 | |
| SCHEMBL7804666 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |