Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813944 | 0.93 | MEN1 (0.61) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7817763 | 0.89 | KMT2A (0.61) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7810142 | 0.88 | POLB (0.60) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7810154 | 0.88 | MEN1 (0.60) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7810093 | 0.88 | MEN1 (0.62) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7810164 | 0.87 | MEN1 (0.58) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7814258 | 0.87 | TSHR (0.61) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7813588 | 0.87 | TSHR (0.58) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7810112 | 0.86 | MEN1 (0.64) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL7813768 | 0.83 | MEN1 (0.51) | SMN1; SMN2TSHRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |