SCHEMBL781161

SCHEMBL781161

c1ccc(-c2cccc(-c3c4ccccc4c(-c4ccccc4-c4ccccc4)c4cc(-n5c6ccccc6c6cc(-c7cccc8c7sc7ccccc78)ccc65)ccc34)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 1/20 0.35
F9 P00740 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745737 0.96 ALOX5 (0.45) ALOX5PRKDCF9
SCHEMBL781016 0.96 ALOX5 (0.45) ALOX5PRKDCF9
SCHEMBL18347201 0.95 ALOX5 (0.44) ALOX5PRKDCF9
SCHEMBL780764 0.93 ALOX5 (0.46) ALOX5PRKDCF9
SCHEMBL768610 0.92 ALOX5 (0.46) ALOX5PRKDCF9
SCHEMBL780862 0.91 ALOX5 (0.46) ALOX5PRKDCF9
SCHEMBL459269 0.91 ALOX5 (0.46) ALOX5PRKDCF9
SCHEMBL780913 0.90 ALOX5 (0.46) ALOX5PRKDC
SCHEMBL780982 0.90 ALOX5 (0.48) ALOX5PRKDCF9
SCHEMBL457804 0.89 ALOX5 (0.46) ALOX5PRKDCF9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885F9 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.