SCHEMBL781194

SCHEMBL781194

c1ccc(-c2cc(-c3ccccc3)c3oc4c(-c5ccc6c7ccc(-c8cc(-c9ccccc9)cc9c8oc8c(-c%10ccccc%10)cc(-c%10ccccc%10)cc89)cc7n(-c7cccc(-c8ccc9c(-c%10ccccc%10)c%10ccccc%10c(-c%10ccccc%10)c9c8)c7)c6c5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.32
PRKDC P78527 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780905 0.98 KDM4E (0.35) PDE10APRKDCKDM4EATML3MBTL1
SCHEMBL781622 0.97 KDM4E (0.32) PDE10APRKDCKDM4EATML3MBTL1
SCHEMBL781034 0.94 KDM4E (0.36) PDE10AKDM4EATML3MBTL1
SCHEMBL780846 0.94 KDM4E (0.35) PDE10APRKDCKDM4EATML3MBTL1
SCHEMBL780981 0.93 PDE10A (0.32) PDE10APRKDCKDM4EATML3MBTL1
SCHEMBL781191 0.93 KDM4E (0.33) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781398 0.93
SCHEMBL780843 0.93 PLA2G2A (0.33) PDE10APRKDCPLA2G2APLA2G4A
SCHEMBL781297 0.92 PRKDC (0.33) PDE10APRKDCKDM4EATML3MBTL1
SCHEMBL18347202 0.92 PDE10A (0.33) PDE10APRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 PDE10A 4667/4885PRKDC 3567/4885KDM4E 3917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.