Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811945 | 0.70 | ATM (0.31) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL5734376 | 0.69 | MAPT (0.32) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL30101244 | 0.65 | ALDH1A1 (0.31) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL793243 | 0.65 | MAPT (0.38) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL6278365 | 0.65 | MAPT (0.35) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL1649691 | 0.65 | MAPT (0.38) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL897853 | 0.63 | CDC25B (0.38) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL29161382 | 0.61 | MAPT (0.54) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL1120400 | 0.58 | MAPT (0.38) | MAPTALDH1A1PKMMAPK10NPSR1 | |
| SCHEMBL8890839 | 0.58 | MAPT (0.35) | MAPTALDH1A1PKMMAPK10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595111-B2 | Carbazolone derivatives and process for preparing the same | RICHTER GEDEON VEGYESZET (HU) | 2001-08-16 | — | — | EP | disclosed |
| EP-0595111-B1 | Carbazolone derivatives and process for preparing the same | RICHTER GEDEON VEGYESZET (HU) | 1997-09-10 | — | — | EP | disclosed |
| US-5478949-A | Reacting the starting carbazolone with dialkyl oxalate, then formaldehyde and 2-methylimidazole | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1995-12-26 | — | — | US | disclosed |
| US-5416221-A | ONDANSETRON INTERMEDIATES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1995-05-16 | — | — | US | disclosed |
| EP-0595111-A1 | Carbazolone derivatives and process for preparing the same | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1994-05-04 | — | — | EP | disclosed |