Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131229 | 0.72 | TGM2 (0.31) | TGM2 | |
| SCHEMBL793243 | 0.68 | MAPT (0.38) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL5734376 | 0.66 | MAPT (0.32) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL7811940 | 0.65 | MAPT (0.33) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL7811945 | 0.64 | ATM (0.31) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL1820520 | 0.63 | ALDH1A1 (0.33) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL29161382 | 0.63 | MAPT (0.54) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL4555854 | 0.61 | — | — | |
| SCHEMBL8890839 | 0.60 | MAPT (0.35) | ALDH1A1MAPTMEN1LMNAPOLB | |
| SCHEMBL4132834 | 0.59 | MAPT (0.37) | ALDH1A1MAPTMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | C5, C1S, CLIC4 | ALDH1A1 4269/4885MAPT 2985/4885MEN1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.