SCHEMBL7812224

SCHEMBL7812224

OB(O)Oc1sccc1Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27684976 0.76 POLB (0.31)
SCHEMBL1942869 0.74 CYP2A6 (0.34) MAPT
SCHEMBL5435189 0.71 CYP2A6 (0.36)
SCHEMBL2824560 0.71 CYP2A6 (0.31)
SCHEMBL7809779 0.68 MEN1 (0.36) MAPT
SCHEMBL4636562 0.68 MAPT (0.40) MAPT
SCHEMBL2183638 0.67
SCHEMBL27680682 0.67 KMT2A (0.41) MAPT
SCHEMBL15056035 0.66 GABRA1 (0.33)
SCHEMBL5260752 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed