SCHEMBL7812253

SCHEMBL7812253

Fc1cccc(F)c1C1=NC(COc2ccc(-c3ccccc3)cc2Cl)CO1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.38
FFAR4 Q5NUL3 1/20 0.36
NR1H4 Q96RI1 1/20 0.35
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995880 0.94 TAAR1 (0.40) TAAR1NPC1RAB9A
SCHEMBL7803418 0.93 TAAR1 (0.38) TAAR1
SCHEMBL7803444 0.92 TAAR1 (0.36) TAAR1FFAR4
SCHEMBL7808652 0.90 PTGES (0.36) TAAR1
SCHEMBL7812270 0.88 TAAR1 (0.36) TAAR1
SCHEMBL7803706 0.84 TAAR1 (0.43) TAAR1MAPT
SCHEMBL7812313 0.83 TAAR1 (0.40) TAAR1FFAR4NPC1POLBRAB9A
SCHEMBL7803613 0.82 MARS1 (0.38) TAAR1FFAR4
SCHEMBL7816156 0.82 TAAR1 (0.51) TAAR1
SCHEMBL7812996 0.79 TAAR1 (0.47) TAAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed