Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | SDHA | P31040 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805454 | 0.86 | MAOA (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7815497 | 0.83 | MAOA (0.50) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7818376 | 0.81 | MAOA (0.44) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8791315 | 0.81 | MAOA (0.43) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8359085 | 0.78 | MAOA (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8359082 | 0.78 | MAOA (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7812586 | 0.76 | MAOA (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8128001 | 0.73 | MAOA (0.38) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7985431 | 0.73 | MAOA (0.40) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5219360 | 0.70 | MAOA (0.38) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788498-B1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0788498-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013502-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |