Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809443 | 0.74 | RXFP1 (0.47) | RXFP1KDM4ECDK1CCNB1DAO | |
| SCHEMBL7813741 | 0.73 | KDM4E (0.45) | KDM4EDAOALDH1A1MEN1KMT2A | |
| SCHEMBL7809440 | 0.71 | RXFP1 (0.40) | RXFP1KDM4ECDK1CCNB1DAO | |
| SCHEMBL7803965 | 0.68 | RXFP1 (0.52) | RXFP1KDM4ECDK1CCNB1DAO | |
| SCHEMBL7812826 | 0.66 | KDM4E (0.38) | KDM4EDAOALDH1A1MEN1KMT2A | |
| SCHEMBL8239577 | 0.66 | FEN1 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7810952 | 0.64 | RXFP1 (0.47) | RXFP1KDM4EDAODYRK1ANR4A2 | |
| SCHEMBL14017831 | 0.62 | NR4A2 (0.43) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3641835 | 0.62 | DAO (0.49) | RXFP1KDM4EDAOMEN1KMT2A | |
| SCHEMBL6991969 | 0.62 | DYRK1A (0.44) | RXFP1KDM4ECDK1CCNB1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| US-5430153-A | Insecticides, fungicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-04 | — | — | US | disclosed |
| EP-0533882-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |