Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998461 | 0.81 | KDM4E (0.49) | L3MBTL1DAOMEN1KMT2AHPGD | |
| SCHEMBL3641835 | 0.80 | DAO (0.49) | DYRK1AL3MBTL1DAOMEN1KMT2A | |
| SCHEMBL20669916 | 0.76 | DAO (0.59) | DAOMEN1KMT2AHPGDKDM4E | |
| SCHEMBL19846959 | 0.72 | DYRK1A (0.55) | DYRK1AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL29432610 | 0.72 | DYRK1A (0.55) | DYRK1AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL6991966 | 0.70 | MEN1 (0.52) | DYRK1AMEN1KMT2AHPGDKDM4E | |
| SCHEMBL18509923 | 0.69 | L3MBTL1 (0.46) | DYRK1AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL3383227 | 0.69 | MAPT (0.55) | DYRK1AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL14566728 | 0.68 | DAO (0.53) | DYRK1ADAOKDM4EPARP1MAP2 | |
| SCHEMBL4076852 | 0.68 | KDM4E (0.62) | DYRK1AL3MBTL1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |