Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812826 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7813019 | 0.73 | RXFP1 (0.40) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7809691 | 0.72 | CAPN1 (0.43) | KDM4ELMNAPOLBHPGDALDH1A1 | |
| SCHEMBL7809500 | 0.71 | KDM4E (0.45) | KDM4ETSHRLMNAPOLBHPGD | |
| SCHEMBL5809605 | 0.69 | RPA1 (0.49) | KDM4ETSHRLMNAPOLBHPGD | |
| SCHEMBL7809496 | 0.68 | KDM4E (0.43) | KDM4ETSHRLMNAPOLBHPGD | |
| SCHEMBL7813191 | 0.66 | NPC1 (0.38) | KDM4ETSHRLMNAPOLBHPGD | |
| SCHEMBL11007640 | 0.66 | KMT2A (0.46) | KDM4ETSHRLMNAPOLBHPGD | |
| SCHEMBL14355040 | 0.64 | KIF11 (0.53) | KDM4ETSHRLMNAPOLBHPGD | |
| SCHEMBL10037103 | 0.63 | TDP1 (0.44) | KDM4ETSHRLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| US-5430153-A | Insecticides, fungicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-04 | — | — | US | disclosed |