Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.63 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ATIC | P31939 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813054 | 1.00 | RPS6KA3 (0.63) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL8843749 | 0.86 | PHLPP2 (0.75) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL8843743 | 0.86 | PHLPP2 (0.75) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL4280752 | 0.84 | PTGS1 (0.74) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL12486693 | 0.83 | RPS6KA3 (0.62) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL12486691 | 0.83 | RPS6KA3 (0.62) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL5357061 | 0.82 | RPS6KA3 (0.58) | RPS6KA3PHLPP2POLBCYP2D6BRD4 | |
| SCHEMBL6256568 | 0.82 | KMT2A (0.71) | POLBCYP2D6BRD4PTGS2PTGS1 | |
| SCHEMBL6256564 | 0.82 | KMT2A (0.71) | POLBCYP2D6BRD4PTGS2PTGS1 | |
| SCHEMBL12486810 | 0.81 | RPS6KA3 (0.56) | RPS6KA3PHLPP2POLBCYP2D6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | claimed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | claimed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-5486214-A | MONO OR DISAZO DYES, LIGNIN PEROXIDASE AND VERATRYL ALCOHOL MIXTURE FOR DEGRADATION OF DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | disclosed |